Article
The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation.
The Journal of biological chemistry - 26 Dec 2003
Moraitis Anna N, Giguère Vincent
Abstract excerpt
RORalpha is a constitutively active orphan nuclear receptor essential for cerebellar development and is previously shown to regulate genes involved in both myogenesis and adipogenesis. The transcriptional activity of RORalpha is dependent on the presence of a ubiquitous ligand and can be abolishe...
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