Article
Carbonic anhydrase-related protein is a novel binding protein for inositol 1,4,5-trisphosphate receptor type 1.
The Biochemical journal - 1 Jun 2003
Hirota Junji, Ando Hideaki, Hamada Kozo, Mikoshiba Katsuhiko
Abstract excerpt
The inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R) is an intracellular IP(3)-gated Ca(2+) channel that is located on intracellular Ca(2+) stores and modulates Ca(2+) signalling. Using the yeast two-hybrid system, we screened a mouse brain cDNA library with bait constructs for mouse IP(3)R...
Topics
- Animals
- Blotting, Western
- Calcium Channels
- Carbonic Anhydrases
- Cerebellum
- DNA Primers
- Gene Library
- Immunoenzyme Techniques
- Inositol 1,4,5-Trisphosphate
- Inositol 1,4,5-Trisphosphate Receptors
- Mice
- Mutagenesis, Site-Directed
