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Article

Expression of the Proto-Oncogene Axl in Renal Cell Carcinoma

1 Aug 2003

Abstract excerpt

In this investigation, we examined the role of the Axl proto-oncogene in renal cell carcinoma (RCC). Axl is a tyrosine kinase receptor implicated in myeloid leukogenesis, and has been found to be overexpressed in lung cancers and breast cancers. Axl has been described to act as a mitogenic factor along with its ligand Gas-6. Axl has also shown to have a role in apoptosis, cell adhesion, and chemotaxis. The...

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PMID: 14565870
DOI: 10.1089/10445490360708946

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