Article
Effect of Atm disruption on spontaneously arising and radiation-induced deletion mutations in mouse liver.
Radiation research - 1 Nov 2003
Furuno-Fukushi Ikuko, Masumura Ken-ichi, Furuse Takeshi, Noda Yuko, Takahagi Masahiko, Saito Toshiyuki, Hoki Yuko, Suzuki Hiroshi, Wynshaw-Boris Anthony, Nohmi Takehiko, Tatsumi Kouichi
Abstract excerpt
Deletion mutations were efficiently recovered in mouse liver after total-body irradiation with X rays by using a transgenic mouse "gpt-delta" system that harbored a lambda EG10 shuttle vector with the red and gam genes for Spi- (sensitive to P2 lysogen interference) selection. We incorporated thi...
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