Article
Estrogen receptor-alpha polymorphisms and angiographic outcome after coronary artery stenting.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2003
Ferrero Valeria, Ribichini Flavio, Matullo Giuseppe, Guarrera Simonetta, Carturan Sonia, Vado Antonello, Vassanelli Corrado, Piazza Alberto, Uslenghi Eugenio, Wijns William
Abstract excerpt
OBJECTIVE: Because of the receptor-mediated antiproliferative effects of estradiol on vascular smooth muscle cells, our study aimed at identifying a role of PvuII and XbaI polymorphisms of the alpha-estrogen receptor (alphaER) gene in the occurrence of restenosis after coronary stent implantation (in-stent restenosis [ISR]). METHODS AND RESULTS: In 858 patients (148 women), 955 lesions were treated with stent...
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