Article
Association of an A allele for interleukin-10 -627 gene promoter polymorphism with higher susceptibility to endometriosis.
The Journal of reproductive medicine - 1 Sept 2003
Hsieh Yao-Yuan, Chang Chi-Chen, Tsai Fuu-Jen, Lin Cheng-Chieh, Tai Chin-Tao, Ho Min
Abstract excerpt
OBJECTIVE: To investigate whether interleukin-10 (IL-10) -627 gene promoter polymorphism could be used as a marker of susceptibility to endometriosis. STUDY DESIGN: Women were divided into 2 groups, endometriosis (n = 130) and nonendometriosis (n = 133). Polymorphisms for IL-10 -627 gene promoter were amplified by polymerase chain reaction and detected after restriction enzyme digestion. Genotypes and allelic...
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