Article
ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer.
British journal of cancer - 20 Oct 2003
Bernstein J L, Bernstein L, Thompson W D, Lynch C F, Malone K E, Teitelbaum S L, Olsen J H, Anton-Culver H, Boice J D, Rosenstein B S, Børresen-Dale A-L, Gatti R A, Concannon P, Haile R W
Abstract excerpt
Recent reports suggest that two ATM gene mutations, 7271T>G and IVS10-6T>G, are associated with a high risk of breast cancer among multiple-case families. To assess the importance of these two mutations in another 'high-risk' group, young women (under age 51) with multiple primaries, we screened a large population-based series of young women with bilateral breast cancer and compared the frequency of these...
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