Article
[Serotonin and the cardiovascular system: role of the serotoninergic 5-HT 2B receptor].
Bulletin de l'Academie nationale de medecine - 1 Jan 2003
Launay Jean-Marie
Abstract excerpt
Identification of factors controlling myocardial differentiation and proliferation is of great importance for understanding the pathogenesis of congenital heart diseases. The molecular mechanism by which serotonin (5-hydroxytryptamine, 5-HT) regulates embryonic development of heart and cardiovascular functions remained unknown until recently. Inactivation of the 5-HT2B receptor (5-HT2BR) gene leads to embryonic...
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