Article
[The 5-HT2B receptor: a main cardio-pulmonary target of serotonin].
Journal de la Societe de biologie - 1 Jan 2004
Etienne Nelly, Schaerlinger Bérénice, Jaffré Fabrice, Maroteaux Luc
Abstract excerpt
In agreement with previous data in the literature, our results indicate that serotonin, a monoamine neurotransmitter, can also regulate cell proliferation, cell movements and cell differentiation. We have recently shown that serotonin is required for embryonic heart development. Genetic ablation of the 5-HT2B receptor leads to partial embryonic and postnatal lethality with abnormal heart development. Similar...
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