Article
5-hydroxytryptamine receptors in the human cardiovascular system.
Pharmacology & therapeutics - 1 Sept 2006
Kaumann Alberto J, Levy Finn Olav
Abstract excerpt
The human cardiovascular system is exposed to plasma 5-hydroxytryptamine (5-HT, serotonin), usually released from platelets. 5-HT can produce harmful acute and chronic effects. The acute cardiac effects of 5-HT consist of tachycardia (preceded on occasion by a brief reflex bradycardia), increased atrial contractility and production of atrial arrhythmias. Acute inotropic, lusitropic and arrhythmic effects of 5-HT...
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