Article
[Variation in HLA-B27 gene subtypes and susceptibility of ankylosing spondylitis in the Croatian population].
Reumatizam - 1 Jan 2001
Grubić Z, Kerhin-Brkljacić V, Perić P, Cecuk E, Kastelan A
Abstract excerpt
The differences in amino acid residues of HLA-B27 subtypes are minor, but may play role in pathogenesis of ankylosing spondylitis (AS). Aim of this study was to investigate of frequency of B27 subtypes in Croatian AS patients and B27 positive healthy controls. Group of 50 AS patients and 38 B27 positive controls were typed for B27 subtypes by PCR-SSP method. In the group of AS patients we found four subtypes:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.