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Article

Polymorphisms in OPA1 are associated with normal tension glaucoma.

Molecular vision - 22 Sept 2003

Powell Brenda L, Toomes Carmel, Scott Shiela, Yeung Anna, Marchbank Nicola J, Spry Paul G D, Lumb Rosemary, Inglehearn Christopher F, Churchill Amanda J

Abstract excerpt

PURPOSE: [corrected] To confirm whether specific polymorphisms in intron 8 (IVS8) of the OPA1 gene are found more commonly in patients with normal tension glaucoma (NTG) compared to normal controls. METHODS: This is a cohort study of 61 patients with NTG, 49 known healthy controls and 119 individuals from the general population. The DNA sequence was determined at the +4 and +32 positions of IVS8 of the OPA1 gene....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14551537

Genes

OPA1
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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