Article
Investigation of the association between OPA1 polymorphisms and normal-tension glaucoma in Korea.
Journal of glaucoma - 1 Dec 2004
Woo Se Joon, Kim Dong Myung, Kim Ji Yeon, Park Sung Sup, Ko Hyun Soo, Yoo Taiwoo
Abstract excerpt
PURPOSE: OPA1, the gene responsible for autosomal dominant optic atrophy, represents a good candidate gene for normal-tension glaucoma (NTG). Single nucleotide polymorphisms on intervening sequence (IVS) 8 of the OPA1 gene (IVS8+4C>T; +32T>C) were recently found to be strongly associated with NTG in a Caucasian population. We investigated whether these polymorphisms in the OPA1 gene were associated with NTG in...
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