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Article

Mutational analysis of BARD1 in familial breast cancer patients in Japan.

Cancer letters - 8 Oct 2003

Ishitobi Makoto, Miyoshi Yasuo, Hasegawa Seiichi, Egawa Chiyomi, Tamaki Yasuhiro, Monden Morito, Noguchi Shinzaburo

Abstract excerpt

Since BRCA1,which is a breast cancer susceptibility gene, form heterodimers with BARD1, it is speculated that BARD1 mutations might affect the function of BRCA1, contributing to breast carcinogenesis. Thus, in the present study, we have conducted mutational analysis of BARD1 in familial breast cancer patients (n=60) who were tested negative for both BRCA1 and BRCA2 germline mutations. We have been unable to show...

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Source

Identifiers

PMID: 14550946
DOI: 10.1016/s0304-3835(03)00387-2

Genes

BARD1
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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