Article
A cross-sectional study of associations between nonsynonymous mutations of the BARD1 gene and breast cancer in Han Chinese women.
Asia-Pacific journal of public health - 1 Jul 2013
Liu Hui, Zhang Hengwei, Sun Xianfu, He Yaning, Li Juntao, Guo Xuhui
Abstract excerpt
UNLABELLED: The PCR-PIRA and PCR-RFLP techniques were used for BARD1 genotyping. Correlations between gene polymorphisms and the susceptibility to breast cancer were analyzed by logistic regression analysis. RESULTS: showed that compared with the wild type of 378 Arg/Arg of BRAD1, the homozygotic type of 378 Ser/Ser with Arg378Ser site mutation had a protective effect (adjusted odds ratio: 0.628, 95% confidence...
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