Article
Neural crest stem cell and cardiac endothelium defects in the TrkC null mouse.
Molecular and cellular neurosciences - 1 Sept 2003
Youn Y H, Feng J, Tessarollo L, Ito K, Sieber-Blum M
Abstract excerpt
TrkC null mice have multiple cardiac malformations. Since neural crest cells participate in cardiac outflow tract septation, the aim of this study was to determine at the cellular level the putative neural crest defect. We have identified three types of progenitor cells: stem cells that undergo self-renewal and can generate many cell types, cells that are restricted in their developmental potentials, and cells...
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