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Article

Detection of katG Ser315Thr substitution in respiratory specimens from patients with isoniazid-resistant Mycobacterium tuberculosis using PCR-RFLP.

Journal of medical microbiology - 1 Nov 2003

Leung Eric Tung-Yiu, Kam Kai-Man, Chiu Agatha, Ho Pak-Leung, Seto Wing-Hong, Yuen Kwok-Yung, Yam Wing-Cheong

Abstract excerpt

Mutations in the katG locus of catalase peroxidase in Mycobacterium tuberculosis (MTB) account for major isoniazid (INH) resistance. In the South China region, a collection of 906 respiratory specimens and 142 MTB isolates was used to evaluate the sensitivity and specificity of a PCR-RFLP method for the detection of INH resistance-associated mutations. Except for four catalase-negative MTB isolates, katG PCR for...

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Identifiers

PMID: 14532345
DOI: 10.1099/jmm.0.05223-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Detection of katG Ser315Thr substitution in respiratory specimens from patients with isoniazid-resistant Mycobacterium tuberculosis using PCR-RFLP.PMID 14532345Read ↗

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