Article
Pathobiology of pulmonary arterial hypertension.
The European respiratory journal - 1 Dec 2002
Eddahibi S, Morrell N, d'Ortho M P, Naeije R, Adnot S
Abstract excerpt
Recent years have witnessed important advances in the understanding of the pathophysiology of primary pulmonary hypertension (PPH). Both genetic and mechanistic studies have succeeded in identifying new molecular pathways relevant to the process of pulmonary vascular remodelling, which underlies PPH. Mutations in the type II bone morphogenetic protein (BMP) receptor (BMPR)-II are now considered to be the genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.