Article
Frequent expression of KIT in endometrial stromal sarcoma with YWHAE genetic rearrangement.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2014
Lee Cheng-Han, Hoang Lien N, Yip Stephen, Reyes Carolina, Marino-Enriquez Adrian, Eilers Grant, Tao Derrick, Chiang Sarah, Fletcher Jonathan A, Soslow Robert A, Nucci Marisa R, Oliva Esther
Abstract excerpt
Endometrial stromal sarcomas with the YWHAE-NUTM2A/B genetic fusion characteristically contain high-grade round to epithelioid cell component that is strongly and diffusely cyclin D1-positive and it may or may not show an associated low-grade fibroblastic/myxoid cell component. They are clinically more aggressive than endometrial stromal sarcomas with the JAZF1-SUZ12 genetic fusion and frequently demonstrate...
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