Article
Lack of association of DMB polymorphism with insulin-dependent diabetes.
Journal of autoimmunity - 1 Aug 1997
Esposito L, Lampasona V, Bonifacio E, Bosi E, Ferrari M
Abstract excerpt
Considerable evidence exists that the genes coding for the HLA class II DQ molecules in the MHC region are major contributors to genetic susceptibility in insulin-dependent diabetes. Located centromeric to the DQ loci are the genes encoding DMA and DMB, two class II-like molecules which play an essential role in the pathway leading to antigen presentation by HLA class II. In this study we have examined the...
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