Article
Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties.
Genes & development - 15 Mar 2002
Gudjonsson Thorarinn, Villadsen René, Nielsen Helga Lind, Rønnov-Jessen Lone, Bissell Mina J, Petersen Ole William
Abstract excerpt
The epithelial compartment of the human breast comprises two distinct lineages: the luminal epithelial and the myoepithelial lineage. We have shown previously that a subset of the luminal epithelial cells could convert to myoepithelial cells in culture signifying the possible existence of a progenitor cell. We therefore set out to identify and isolate the putative precursor in the luminal epithelial compartment....
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