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Article

Uromodulin: old friend with new roles in health and disease.

Pediatric nephrology (Berlin, Germany) - 1 Jul 2014

Iorember Franca M, Vehaskari V Matti

Abstract excerpt

The most abundant urinary protein, Tamm-Horsfall protein, later renamed uromodulin, is expressed exclusively by the thick ascending limb cells of the kidney and released into urine from the apical cell membrane. Uromodulin is believed to protect against urinary tract infections and stones, but its other physiologic functions have remained obscure until recently. Renewed interest in uromodulin has been brought...

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Identifiers

PMID: 23880785
DOI: 10.1007/s00467-013-2563-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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