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Article

Catechol-O-methyltransferase and monoamine oxidase A genotypes and drug response to conventional neuroleptics in schizophrenia.

Journal of clinical psychopharmacology - 1 Oct 2003

Illi Ari, Mattila Kari M, Kampman Olli, Anttila Sami, Roivas Markus, Lehtimäki Terho, Leinonen Esa

Abstract excerpt

Biogenic amine synthesis and degradation are involved in the pathogenesis of schizophrenia. Catechol-O-methyltransferase and monoamine oxidase enzymes are important agents in the metabolic inactivation of these neurotransmitters (ie, dopamine, serotonin, and norepinephrine). Functional polymorphi...

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Identifiers

PMID: 14520117
DOI: 10.1097/01.jcp.0000088916.02635.33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14520117-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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