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Catechol O-methyltransferase and monoamine oxidase A genotypes, and plasma catecholamine metabolites in bipolar and schizophrenic patients.

Neurochemistry international - 1 Jan 2000

Zumárraga Mercedes, Dávila Ricardo, Basterreche Nieves, Arrue Aurora, Goienetxea Biotza, Zamalloa María I, Erkoreka Leire, Bustamante Sonia, Inchausti Lucía, González-Torres Miguel A, Guimón José

Abstract excerpt

Metabolites of dopamine and norepinephrine measured in the plasma have long been associated with symptomatic severity and response to treatment in schizophrenic, bipolar and other psychiatric patients. Plasma concentrations of catecholamine metabolites are genetically regulated. The genes encoding enzymes that are involved in the synthesis and degradation of these monoamines are candidate targets for this genetic...

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PMID: 20206656
DOI: 10.1016/j.neuint.2010.02.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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