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Article

Fosmidomycin resistance in adenylate cyclase deficient (cya) mutants of Escherichia coli.

Bioscience, biotechnology, and biochemistry - 1 Sept 2003

Sakamoto Yoshiko, Furukawa Soichi, Ogihara Hirokazu, Yamasaki Makari

Abstract excerpt

Adenylate cyclase deficient (cya) mutants of E. coli K-12 were found to be resistant to fosmidomycin, a specific inhibitor of the non-mevalonate pathway, just like to fosfomycin. E. coli glpT mutants were resistant to fosfomycin and also to fosmidomycin. This fact shows that fosmidomycin was transported inside via the glycerol-3-phosphate transporter, GlpT. DNA micro-array analysis showed that the transcription...

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Identifiers

PMID: 14519998
DOI: 10.1271/bbb.67.2030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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