Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of p53 protein core domain structural alteration on ovarian cancer survival.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2003

Rose Stephen L, Robertson Andrew D, Goodheart Michael J, Smith Brian J, DeYoung Barry R, Buller Richard E

Abstract excerpt

PURPOSE: Although survival with a p53 missense mutation is highly variable, p53-null mutation is an independent adverse prognostic factor for advanced stage ovarian cancer. By evaluating ovarian cancer survival based upon a structure function analysis of the p53 protein, we tested the hypothesis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian Neoplasms
Share to Protein Folding
Share to Survival Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Genes, p53

Share to Mutation, Missense

Share to Neoplasm Staging

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 14519637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14519637-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

The impact of p53 protein core domain structural alteration on ovarian cancer survival.PMID 14519637Read ↗

The prognostic significance of p53 tumor suppressor gene alterations in ovarian carcinoma.Semantic proximity Read ↗

Expression signatures of TP53 mutations in serous ovarian cancers.Semantic proximity Read ↗

Prognostic significance of p53 mutation and p53 overexpression in advanced epithelial ovarian cancer: a Gynecologic Oncology Group Study.Semantic proximity Read ↗

Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein.Semantic proximity Read ↗

Prognostic significance of p53 mutation in breast cancer: frequent detection of non-missense mutations by yeast functional assay.Semantic proximity Read ↗

Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer.Semantic proximity Read ↗

p53 mutation is a common genetic event in ovarian carcinoma.Semantic proximity Read ↗

Alteration of p53 gene in ovarian carcinoma: clinicopathological correlation and prognostic significance.Semantic proximity Read ↗

p53 null mutations undetected by immunohistochemical staining predict a poor outcome with early-stage non-small cell lung carcinomas.Semantic proximity Read ↗

Distant metastases in ovarian cancer: association with p53 mutations.Semantic proximity Read ↗

P53 mutation does not affect prognosis in ovarian epithelial malignancies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.