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Article

TBX5 nuclear localization is mediated by dual cooperative intramolecular signals.

Journal of molecular and cellular cardiology - 1 Oct 2003

Collavoli Anita, Hatcher Cathy J, He Jie, Okin Daniel, Deo Rahul, Basson Craig T

Abstract excerpt

The TBX5 transcription factor is required for normal cardiogenesis, and human TBX5 mutations cause congenital heart defects. Previous studies have shown that TBX5 can localize to cellular nuclei during embryogenesis and have suggested that altered nuclear localization may contribute to disease pa...

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Source

Identifiers

PMID: 14519429
DOI: 10.1016/s0022-2828(03)00231-1

Genes

TBX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14519429-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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TBX5 nuclear localization is mediated by dual cooperative intramolecular signals.PMID 14519429Read ↗

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