Article
A simple signal element mediates transcription termination and mRNA 3' end formation in the DEG1 gene of Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 1 May 1997
Brambilla A, Mainieri D, Agostoni Carbone M L
Abstract excerpt
DEG1 is a weakly transcribed gene of Saccharomyces cerevisiae, closely associated with CEN6. We mapped its major poly(A) site only 24 nucleotides (nt) downstream of the stop codon, and only 26 nt upstream of the CDEI centromere element. The deletion of this 50 nt stretch completely abolishes formation of the mRNA 3' end. A shorter deletion of a 16 nt sequence in the 3'-untranslated region has the same effect on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
