Article
Capillarization of hepatic sinusoid by liver endothelial cell-reactive autoantibodies in patients with cirrhosis and chronic hepatitis.
The American journal of pathology - 1 Oct 2003
Xu Bo, Broome Ulrika, Uzunel Mehmet, Nava Silvia, Ge Xupeng, Kumagai-Braesch Makiko, Hultenby Kjell, Christensson Birger, Ericzon Bo-Göran, Holgersson Jan, Sumitran-Holgersson Suchitra
Abstract excerpt
The special features of liver sinusoidal endothelium (LSE) are crucial for normal liver physiology. Cirrhotic livers, especially in primary biliary cirrhosis (PBC), are characterized by transformation of the LSE into a continuous, vascular type. The transformation is important for disease progression and explains some of the pathological hallmarks of the cirrhotic liver. Here, we investigated the presence of...
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