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Article

Astrocyte characterization in the multiple sclerosis glial scar.

Neuropathology and applied neurobiology - 1 Oct 2003

Holley J E, Gveric D, Newcombe J, Cuzner M L, Gutowski N J

Abstract excerpt

Dense astrocytic scarring in chronic multiple sclerosis (MS) plaques produces an inhibitory environment which can impede tissue repair. Animal studies have shown that the antigenic phenotype of the most abundant cell type in the brain, the astrocyte, varies depending on astrocyte type and location. To identify the phenotype of scar astrocytes (SAs) in chronic lesions, markers of reactive astrocytes characterized...

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Identifiers

PMID: 14507335
DOI: 10.1046/j.1365-2990.2003.00491.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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