Article
Human cytomegalovirus chemokine receptor US28-induced smooth muscle cell migration is mediated by focal adhesion kinase and Src.
The Journal of biological chemistry - 12 Dec 2003
Streblow Daniel N, Vomaske Jennifer, Smith Patsy, Melnychuk Ryan, Hall Laurel, Pancheva Dora, Smit Martine, Casarosa Paola, Schlaepfer David D, Nelson Jay A
Abstract excerpt
The human cytomegalovirus-encoded chemokine receptor US28 induces arterial smooth muscle cell (SMC) migration; however, the underlying mechanisms involved in this process are unclear. We have previously shown that US28-mediated SMC migration occurs by a ligand-dependent process that is sensitive to protein-tyrosine kinase inhibitors. We demonstrate here that US28 signals through the non-receptor protein-tyrosine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
