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Human cytomegalovirus open reading frame US28 encodes a functional beta chemokine receptor.

1 Nov 1994

Abstract excerpt

Human cytomegalovirus infects epithelial, smooth muscle, and white blood cells in vivo causing acute, latent, and chronic infections. A data base search revealed that the amino acid sequence of the putative protein encoded by open reading frame US28 of human cytomegalovirus is approximately 30% identical to those of the mammalian leukocyte receptors for alpha and beta chemokines. This suggested that US28 was...

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PMID: 7961796
DOI: 10.1016/s0021-9258(19)61936-8

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