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Article

A human homolog of the yeast gene encoding tRNA 2'-phosphotransferase: cloning, characterization and complementation analysis.

Cellular and molecular life sciences : CMLS - 1 Aug 2003

Hu Q-D, Lu H, Huo K, Ying K, Li J, Xie Y, Mao Y, Li Y-Y

Abstract excerpt

The Saccharomyces cerevisiae TPT1 gene plays a role in removing the 2'-phosphate from ligated tRNA during the maturation of pre-tRNA. Here we reported the cloning and characterization of the human TRPT1 gene as a homolog of yeast TPT1. The TRPT1 gene is located at human chromosome 11q13 and encodes a polypeptide of 253 amino acids. BLAST searches with its amino acid sequence revealed the ubiquitous occurrence of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Phosphotransferases (Alcohol Group Acceptor)

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Source

Open in PubMed Open full text

Identifiers

PMID: 14504659
DOI: 10.1007/s00018-003-3107-7
PMCID: PMC11138648

Genes

TRPT1
TPT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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