Exploring population size changes using SNP frequency spectra.

doi:10.1038/ng.3254

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Exploring population size changes using SNP frequency spectra.

Nature genetics - 1 May 2015

Liu Xiaoming, Fu Yun-Xin

Abstract excerpt

Inferring demographic history is an important task in population genetics. Many existing inference methods are based on predefined simplified population models, which are more suitable for hypothesis testing than exploratory analysis. We developed a novel model-flexible method called stairway plot, which infers changes in population size over time using SNP frequency spectra. This method is applicable for...

Topics

Algorithms
Gene Frequency
Genome, Human
Haplotypes
Humans
Models, Genetic
Polymorphism, Single Nucleotide
Population Dynamics

Source

Open in PubMed Open full text

Identifiers

PMID: 25848749
DOI: 10.1038/ng.3254
PMCID: PMC4414822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics