Article
Sweat gland innervation is pioneered by sympathetic neurons expressing a cholinergic/noradrenergic co-phenotype in the mouse.
Neuroscience - 2 Oct 2008
Schütz B, von Engelhardt J, Gördes M, Schäfer M K-H, Eiden L E, Monyer H, Weihe E
Abstract excerpt
Classic neurotransmitter phenotypes are generally predetermined and develop as a consequence of target-independent lineage decisions. A unique mode of target-dependent phenotype instruction is the acquisition of the cholinergic phenotype in the peripheral sympathetic nervous system. A body of work suggests that the sweat gland plays an important role to determine the cholinergic phenotype at this target site. A...
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