Article
Changes in apolipoprotein E expression in response to dietary and pharmacological modulation of cholesterol.
Journal of molecular neuroscience : MN - 1 Jan 2003
Petanceska Suzana S, DeRosa Steven, Sharma Ali, Diaz Nichole, Duff Karen, Tint Steven G, Refolo Lorenzo M, Pappolla Miguel
Abstract excerpt
Apolipoprotein E (ApoE) influences the risk of late onset Alzheimer's disease (AD) in an isoform-dependent manner, such that the presence of the apoE epsilon4 allele increases the risk of AD while the presence of the apoE epsilon2 allele appears to be protective. Although a number of ApoE functio...
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