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Genetic Variants Associated With Alzheimer Disease in the 22 Arab Countries: A Systematic Review.

Alzheimer disease and associated disorders - 1 Jan 2000

Al-Thani Hissa F, Ahmad Muneera N, Younes Salma, Zayed Hatem

Abstract excerpt

BACKGROUND AND AIMS: Alzheimer disease (AD) is a progressive and complex neurodegenerative disease. Approximately 70% of AD risk is attributed to genetic risk factors, including variants in amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2) genes. Several studies have revealed a considerable number of candidate loci and genes for AD among different ethnic populations. However, the...

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PMID: 33769987
DOI: 10.1097/WAD.0000000000000447

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