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Article

Role of luxS in immune evasion and pathogenicity of piscine Streptococcus agalactiae is not dependent on autoinducer-2.

Fish & shellfish immunology - 1 Apr 2020

Cao Qing, Ma Ke, Nie Meng, Dong Yuhao, Lu Chengping, Liu Yongjie

Abstract excerpt

luxS-mediated autoinducer 2 (AI-2)-dependent quorum sensing (QS) has been demonstrated to affect many bacterial phenotypes, including virulence. Streptococcus agalactiae harbors a functional luxS gene required for the biosynthesis of AI-2. In this study, we investigated the regulation effect and mechanism of the luxS/AI-2 QS system in the pathogenicity of the piscine S. agalactiae strain GD201008-001. We found...

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PMID: 32058098
DOI: 10.1016/j.fsi.2020.02.016

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