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Article

Adult onset spinocerebellar ataxia linked to HLA in a South African kindred of mixed ancestry.

Tissue antigens - 1 Sept 1992

Bryer A, Martell R W, du Toit E D, Beighton P

Abstract excerpt

Hereditary spinocerebellar ataxia (SCA) is a relatively common disorder in the Western Cape region of South Africa. At present there are no genetic markers available for prenatal or presymptomatic diagnosis. A large kindred of mixed ancestry with late onset SCA was studied in which the disorder segregated in an autosomal dominant fashion. HLA typing was undertaken on 44 family members, and the HLA haplotypes were...

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Identifiers

PMID: 1440565
DOI: 10.1111/j.1399-0039.1992.tb02101.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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