Absence of close linkage between maternal genes for susceptibility to pre-eclampsia/eclampsia and HLA DR beta.

doi:10.1016/0140-6736(90)92149-c

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Article

Absence of close linkage between maternal genes for susceptibility to pre-eclampsia/eclampsia and HLA DR beta.

Lancet (London, England) - 15 Sept 1990

Wilton A N, Cooper D W, Brennecke S P, Bishop S M, Marshall P

Abstract excerpt

To test the possibility that maternally expressed susceptibility genes for pre-eclampsia/eclampsia are closely linked to the HLA region on chromosome 6 of the human genome, members of ten pedigrees with multiple cases of these disorders were typed for HLA DR beta restriction fragment length polym...

Topics

Adult
Chromosome Mapping
Chromosomes, Human, Pair 6
Disease Susceptibility
Eclampsia
Electrophoresis, Agar Gel
Evaluation Studies as Topic
Female
Genetic Carrier Screening
Genetic Linkage
Genetic Markers
HLA-DR Antigens
Humans
Lod Score
Pedigree
Phenotype
Polymorphism, Restriction Fragment Length
Pre-Eclampsia

Source

Open in PubMed

Identifiers

PMID: 1975853
DOI: 10.1016/0140-6736(90)92149-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1975853-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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