Article
Localization of the hemochromatosis gene close to D6S105.
American journal of human genetics - 1 Aug 1993
Jazwinska E C, Lee S C, Webb S I, Halliday J W, Powell L W
Abstract excerpt
The hemochromatosis (HC) gene is known to be linked to HLA-A (6p21.3); however, its precise location has been difficult to determine because of a lack of additional highly polymorphic markers for this region. The recent identification of short tandem repeat sequences (microsatellites) has now pro...
Topics
- Adolescent
- Adult
- Alleles
- Chi-Square Distribution
- Child
- Chromosome Mapping
- Chromosomes, Human, Pair 6
- DNA, Satellite
- Gene Frequency
- Genetic Linkage
- Genetic Markers
- HLA-A Antigens
- HLA-B Antigens
- Hemochromatosis
- Humans
- Lod Score
- Middle Aged
- Pedigree