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Article

Localization of the hemochromatosis gene close to D6S105.

American journal of human genetics - 1 Aug 1993

Jazwinska E C, Lee S C, Webb S I, Halliday J W, Powell L W

Abstract excerpt

The hemochromatosis (HC) gene is known to be linked to HLA-A (6p21.3); however, its precise location has been difficult to determine because of a lack of additional highly polymorphic markers for this region. The recent identification of short tandem repeat sequences (microsatellites) has now provided this area with a number of markers with similar polymorphic index to the HLA serological polymorphisms. Using...

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Identifiers

PMID: 8328453
PMCID: PMC1682361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Localization of the hemochromatosis gene close to D6S105.PMID 8328453Read ↗

Allelic association of microsatellites of 6p in Italian hemochromatosis patients.Semantic proximity Read ↗

Isolation of CA dinucleotide repeats close to D6S105; linkage disequilibrium with haemochromatosis.Semantic proximity Read ↗

New polymorphic microsatellite markers place the haemochromatosis gene telomeric to D6S105.Semantic proximity Read ↗

Allelic associations and homozygosity at loci from HLA-B to D6S299 in genetic haemochromatosis.Semantic proximity Read ↗

The gene for autosomal dominant spinocerebellar ataxia (SCA1) maps centromeric to D6S89 and shows no recombination, in nine large kindreds, with a dinucleotide repeat at the AM10 locus.Semantic proximity Read ↗

A detailed physical map of the 6p reading disability locus, including new markers and confirmation of recombination suppression.Semantic proximity Read ↗

The gene for autosomal dominant spinocerebellar ataxia (SCA1) maps telomeric to the HLA complex and is closely linked to the D6S89 locus in three large kindreds.Semantic proximity Read ↗

Genetics of haemochromatosis.Semantic proximity Read ↗

Conservation of ancestral haplotypes telomeric of HLA-A.Semantic proximity Read ↗

Construction of a genetic map telomeric to HLA-A by microsatellite analysis.Semantic proximity Read ↗

Anonymous marker loci within 400 kb of HLA-A generate haplotypes in linkage disequilibrium with the hemochromatosis gene (HFE)Semantic proximity Read ↗

Haplotype analysis in Australian hemochromatosis patients: evidence for a predominant ancestral haplotype exclusively associated with hemochromatosis.Semantic proximity Read ↗

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