Article
The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains.
The Journal of cell biology - 1 Nov 1992
Vater C A, Raymond C K, Ekena K, Howald-Stevenson I, Stevens T H
Abstract excerpt
The product of the VPS1 gene, Vps1p, is required for the sorting of soluble vacuolar proteins in the yeast Saccharomyces cerevisiae. We demonstrate here that Vps1p, which contains a consensus tripartite motif for guanine nucleotide binding, is capable of binding and hydrolyzing GTP. Vps1p is a me...
Topics
- Ca(2+) Mg(2+)-ATPase
- Carrier Proteins
- Drosophila Proteins
- Dynamins
- Fungal Proteins
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Genes, Fungal
- Guanosine Triphosphate
- Microtubules
- Mutagenesis
- Phenotype
- Point Mutation
- Saccharomyces cerevisiae
- Temperature