Article
ERG10 from Saccharomyces cerevisiae encodes acetoacetyl-CoA thiolase.
The Journal of biological chemistry - 16 Dec 1994
Hiser L, Basson M E, Rine J
Abstract excerpt
Two recessive alleles of ERG10 and three temperature-sensitive recessive alleles of HMG1 (3-hydroxy-3-methyl-glutaryl-CoA reductase isoenzyme 1) were isolated in a screen for mevalonate auxotrophs in Saccharomyces cerevisiae. The essential, single-copy ERG10 gene was cloned by complementation of...
Topics
- Acetyl-CoA C-Acetyltransferase
- Alleles
- Amino Acid Sequence
- Binding Sites
- Cloning, Molecular
- Consensus Sequence
- Cytoplasm
- DNA, Fungal
- Genes, Fungal
- Genetic Complementation Test
- Mevalonic Acid
- Molecular Sequence Data
- Mutagenesis, Insertional
- Restriction Mapping
- Saccharomyces cerevisiae
- Sequence Alignment
- Sequence Homology, Amino Acid