Article
Peroxisomal degradation of trans-unsaturated fatty acids in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry - 12 Jan 2001
Gurvitz A, Hamilton B, Ruis H, Hartig A
Abstract excerpt
Degradation of trans-unsaturated fatty acids was studied in the yeast Saccharomyces cerevisiae. Propagation of yeast cells on trans-9 elaidic acid medium resulted in transcriptional up-regulation of the SPS19 gene, whose promoter contains an oleate response element. This up-regulation depended on the Pip2p-Oaf1p transcription factor and was accompanied by induction of import-competent peroxisomes. Utilization of...
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