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Article

Expression of resistance to etoposide and vincristine in vitro and in vivo after X-irradiation of ovarian tumor cells.

Anti-cancer drugs - 1 Aug 1992

Dempke W C, Whelan R D, Hill B T

Abstract excerpt

Two human ovarian carcinoma cell lines (JA-T/P and SK-OV-3/P) were exposed to 10 fractions of 5 Gy X-irradiation in vitro. Surviving populations generated sublines designated DXR-10 which expressed significant resistance to etoposide (VP-16) and vincristine (VCR), but not to adriamycin (ADR) or acute X-irradiation, as judged by clonogenic assays. JA-T/P and JA-T/DXR-10 tumor cells were xenografted into nude mice...

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Identifiers

PMID: 1421436
DOI: 10.1097/00001813-199208000-00013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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