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Article

Autoantibodies against a serine tRNA-protein complex implicated in cotranslational selenocysteine insertion.

15 Oct 1992

Abstract excerpt

We describe an autoantibody specificity present in a subgroup of patients with a severe form of autoimmune chronic active hepatitis. These antibodies precipitate a 90-nucleotide RNA from human whole cell extracts and recognize a 48-kDa polypeptide in immunoblotting assays. The RNA is a UGA suppressor serine tRNA that carries selenocysteine (tRNA[Ser]Sec)), as shown by sequence analysis. The protein does not...

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Identifiers

PMID: 1409691
DOI: 10.1073/pnas.89.20.9739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Autoantibodies against a serine tRNA-protein complex implicated in cotranslational selenocysteine insertion.PMID 1409691Read ↗

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