Article
[Novel autoantibodies that recognize native transfer RNAs in patients with systemic rheumatic diseases].
Ryumachi. [Rheumatism] - 1 Aug 1997
Matsumura M, Ohosone Y, Ishida M, Takahashi Y, Hirakata M, Mimori T
Abstract excerpt
Autoantibodies directed against aminoacyl-tRNA synthetases are well described in adult polymyositis/dermatomyositis. However, the characteristics of antibodies against other tRNA and tRNA-associated proteins have not been well defined. In this study, we identified novel autoantibodies to total tRNAs in patients with systemic rheumatic diseases and characterized the structure that was recognized by anti-tRNA...
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