Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human anti-asparaginyl-tRNA synthetase autoantibodies (anti-KS) increase the affinity of the enzyme for its tRNA substrate.

FEBS letters - 13 Apr 2001

Beaulande M, Kron M, Hirakata M, Härtlein M

Abstract excerpt

Autoantibodies directed against specific human aminoacyl-tRNA synthetases have been associated with a clinical picture including myositis, arthritis, interstitial lung disease and other features that has been referred to as the "anti-synthetase syndrome". Anti-asparaginyl-tRNA synthetase autoantibodies (anti-KS), the most recently described anti-synthetase autoantibodies, are directed against human cytosolic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acylation
Share to Amino Acyl-tRNA Synthetases
Share to Antibody Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aspartate-tRNA Ligase

Share to Epitope Mapping

Share to Immune Sera

Share to Neutralization Tests

Share to RNA, Transfer, Amino Acyl

Source

Identifiers

PMID: 11311235
DOI: 10.1016/s0014-5793(01)02340-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human anti-asparaginyl-tRNA synthetase autoantibodies (anti-KS) increase the affinity of the enzyme for its tRNA substrate.PMID 11311235Read ↗

Aminoacyl-tRNA Synthetases: On Anti-Synthetase Syndrome and BeyondSemantic proximity Read ↗

Autoantigenic properties of the aminoacyl tRNA synthetase family in idiopathic inflammatory myopathiesSemantic proximity Read ↗

Antisynthetase syndrome: A distinct disease spectrumSemantic proximity Read ↗

Aminoacyl-tRNA synthetases: Structure, function, and drug discovery.Semantic proximity Read ↗

Common and Distinct Clinical Features in Adult Patients with Anti-Aminoacyl-tRNA Synthetase Antibodies: Heterogeneity within the SyndromeSemantic proximity Read ↗

[Novel autoantibodies that recognize native transfer RNAs in patients with systemic rheumatic diseases].Semantic proximity Read ↗

The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodiesSemantic proximity Read ↗

Generation and validation of recombinant antibodies to study human aminoacyl-tRNA synthetasesSemantic proximity Read ↗

Clinical, radiological, and pathological features of anti-asparaginyl tRNA synthetase antibody-related interstitial lung diseaseSemantic proximity Read ↗

Interstitial lung disease with autoantibodies againstaminoacyl-tRNA synthetases in the absence of clinically apparent myositisSemantic proximity Read ↗

[Clinical phenotypes and prognosis of antisynthetase syndrome].Semantic proximity Read ↗

A motif in human histidyl-tRNA synthetase which is shared among several aminoacyl-tRNA synthetases is a coiled-coil that is essential for enzymatic activity and contains the major autoantigenic epitope.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.