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Article

Metabolism of plasma low density lipoproteins in familial combined hyperlipidaemia: effect of acipimox therapy.

Journal of internal medicine - 1 Oct 1992

Ericsson S, Eriksson M, Berglund L, Angelin B

Abstract excerpt

Ten male patients with familial combined hyperlipidaemia (FCHL) were studied with regard to LDL metabolism and composition. The FCHL patients had higher LDL levels than healthy controls (5.4 +/- 1.4 vs. 3.7 +/- 0.7 mmol l-1; P < 0.005) and a higher rate of production of the lipoprotein (15.8 +/- 3.1 mg kg-1 d-1 in FCHL vs. 13.1 +/- 1.8 mg kg-1 d-1 in the normals; P < 0.005). The fractional catabolic rate of LDL...

Topics

Adult
Aged
Aged, 80 and over
Apolipoproteins B
Cholesterol, HDL
Cholesterol, VLDL
Humans
Hyperlipidemia, Familial Combined
Hypolipidemic Agents
Lipoproteins, LDL
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Phenotype

Pyrazines

Triglycerides

Source

Identifiers

PMID: 1402634
DOI: 10.1111/j.1365-2796.1992.tb00591.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1402634-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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