Article
Effect of aging and obesity on the expression of dyslipidaemia in children from families with familial combined hyperlipidaemia.
Clinical science (London, England : 1979) - 1 Jan 2007
ter Avest Ewoud, Sniderman Allan D, Bredie Sebastian J H, Wiegman Albert, Stalenhoef Anton F H, de Graaf Jacqueline
Abstract excerpt
The aim of the present study was to delineate the mechanism(s) responsible for the increased secretion of VLDL (very-low-density lipoprotein) particles in patients with FCH (familial combined hyperlipidaemia). In 194 young adults (<25 years of age) recruited from families with FCH, we investigated how plasma lipids, (apo)lipoproteins and BMI (body mass index) varied with age. Furthermore, we performed a 5-year...
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